[fisk]

Stable/lego-brick phenotypes: Is this about coming up with something akin to 0 and 1 and then building from the ground up? Or is this about something that's closer to familiar biology but with some fiendishly clever compartmentalization somehow?

[kanzure]

Well, given our tremendous struggle with rational design of novel protein nanostructures, my point was that we should avoid that difficulty by designing some ligand-binding proteins only once, then assemble those into the larger structures that we desire.

Of course, knowing all protein (structural) phenotypes for all amino acid sequences up to length=100 would also be nice... but seems unlikely something we can work towards due to constraints of scarce universe.