[enkephalin]

> no apparent histamine release

a lot of people, including myself, get very itchy from kratom, and i've always attributed that to histamine release. could it be something else?

[GordonS]

I have actually have a condition that means I naturally release too much histamine, so I take a lot of antihistamines. When I take prescribed opioid drugs, e.g. tramadol, dihydrocodeine, mophine, the itching can be absolutely unbearable.

With kratom I don't notice much extra itching at all, but I suppose we all act differently to things.

[philhartmanonic]

That's fascinating, I've never heard of that before. Is it your throat that gets itchy?

[pault]

Skin. It's where the cliche of the junky scratching his arms comes from.