[rotwoof]

>And it seems like tons of meat and cheese is actually bad long term, in the sense it clogs your arteries

This is an inaccurate conclusion based on old studies where the subjects underwent a high-carbohydrate high-fat diet. Recent studies on ketogenic diets (low-carbohydrate, medium-protein, high-fat intake) shows that dietary fats and dietary cholesterol barely make any sort of impact on the subject's cholesterol. Rather it is dietary carbohydrates and genetics which are the primary contributor to raised cholesterol and arterial blockage. When it comes to arterial blockage, studies have found that there is no significant correlation between high dietary fat intake and cardiovascular disease.

>or increases cancer risk

Keto is primarily a high-fat diet, not a high-protein or high-carb diet. Studies have showed that a sugar found in red meats called Neu5Gc is primarily correlated with inflammation in the body and the development of certain cancers.

If you're on keto you're less likely to develop cardiovascular disease, and while there is not enough data yet to draw a scientific conclusion preliminary research indicates that individuals who follow keto are at less risk of developing cancer due to restricting sugar intake.

See: https://www.reddit.com/r/ketoscience/search?q=cancer&restric...

All of these posts link to multiple, verified studies which go into details about what I just said.

[AstralStorm]

What you said about cancer risk or long term safety of the whole class of those diets. Especially anything related to mortality and morbidity endpoints.

Cholesterol numbers are nowhere near the end of story, they're just markers. Rat and mice studies are useless for this purpose.

Please correct me if I am wrong. Preferably with published larger studies. In humans.

[twayamznacct]

>shows that dietary fats and dietary cholesterol barely make any sort of impact on the subject's cholesterol.

>Rather it is dietary carbohydrates and genetics which are the primary contributor to raised cholesterol and arterial blockage. So what about APOE4 individuals, which compose at least 20% of the population, who will see massively spiking LDL with higher saturated fat intake?

Yes, it's based on genetics, but also intrinsically tied to dietary (saturated) fat intake.