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How Heat Kills Cells

83 points| Errorcod3 | 8 years ago |quantamagazine.org

22 comments

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[+] kapuru|8 years ago|reply
What about tanning (or tanning studios)? I know there's a big difference between a sauna and a tanning studio, but since we're talking about heating up the body, would it have the same effect? (...despite causing skin cancer)
[+] matt4077|8 years ago|reply
A sauna does not heat up the body enough to trigger protein denaturation (unless you get locked in and die, which happens to be among my worst nightmares).

Core temperature is tightly regulated, as well. It should be 37degC. Plus or minus just 2 degrees will severely impair function, plus or minus 5 degrees is reason to call 911.

[+] galfarragem|8 years ago|reply
Noob question. Is it possible to explain the benefits of sauna with this research?
[+] twobyfour|8 years ago|reply
Our mammalian bodies go to great lengths to keep our cells at a stable temperature to prevent protein denaturation from killing our cells. Our first line of defense for thermostasis is our circulatory system (to carry extra heat energy away from overheated organs towards the surface where it can dissipate), combined with sweating (to allow evaporative phase change to cool the blood near the skin).

One can argue whether sweating in this context does or does not also carry off toxins. But in addition to its thermoregulatory role, increased circulation is one of the body's natural healing mechanisms. (Out of control increased circulation causing tissue damage is one of the reasons we ice injuries.) It delivers oxygen and nutrients to our cells. Increased circulation in the sauna may be giving the body the chance to deliver more of these things and to repair cells and organs at a higher rate than it might otherwise.

[+] adrianN|8 years ago|reply
Are the benefits of sauna even proven? I'm not aware of any studies that show definite benefits, only "may help with" results.
[+] Shivetya|8 years ago|reply
so how this tie in if at all with the article stating cells can reach 50C in burst while providing energy? https://www.newscientist.com/article/2129849-the-energy-gene...

does this give us the upper limit of the sources we can convert?

[+] JPLeRouzic|8 years ago|reply
I am not a scientist but I think there is a problem in the article that you are correctly (IMO) pointing out. It is that the notion of temperature has not the same meaning at molecular level and at macro level.
[+] retox|8 years ago|reply
Kudos for putting the summary at the very top of the page.

>The proteins that unravel as the temperature starts to rise turn out to be among the most vital.

[+] iplaw|8 years ago|reply
I also appreciated the dynamic progression indicator at the top of the page. Some of these journal articles are organized and written such that there is no end in sight - it's hard to intuitively know where you are in the article, if you are nearly the buried results/conclusion, etc. The simply indicator tracks progress through the article without having to glance at the oft-invisible right-side scrollbar.