First-Ever LSD Microdosing Study Will Pit the Human Brain Against AI

[adrianN]

Gwern did some self-experimentation with LSD and didn't find any significant effects: https://www.gwern.net/LSD%20microdosing

[wslh]

Since this is a sample with n=1, that doesn't mean there is not significant effects in certain population of people.

[tribby]

there were a few problems with gwern's methodology IIRC. didn't test a perceptual dose after dissolving it, and also didn't get energy control (spanish lsd-testing lab) to evaluate potency.

[atom-morgan]

I did and I did.

[danohu]

Amanda Feilding, who this article is about, is a fascinating person. In the 70s she drilled a hole in her own skull ("trepanation"), then ran for political office to promote the benefits of that operation. She's now Countess of Wemyss and March, married to a similarly-trepanned Earl.

http://cabinetmagazine.org/issues/28/turner.php

[factsaresacred]

Trep-a-na-tion, eh? That's new. Let's have a look at the Wikipedia page then.....

https://en.wikipedia.org/wiki/Trepanning#/media/File:Peter_T...

Nope.

[mmagin]

"ran for political office to promote the benefits of that operation"

As if there weren't enough reasons to be afraid of politicians!

[Baeocystin]

'Fascinating' is not the adjective I would use to describe someone enamored with drilling holes through their skull.

[ggggtez]

> drilled a hole in her own head

Ok, you lost me. Anyone willing to do this is clearly outside of human average, and their anecdata is useless

[metaphorm]

Amanda Fielding is certainly an eccentric person. however, she has a decades long commitment to responsible and scientifically grounded research with psychedelics.

[vixen99]

How frustrating given that the rest of us have no hope of trying anything like this.

[SCHiM]

You do know that it's trivial to obtain these drugs (and tests) on tor marketplaces right?

In case you did not, the alphabay sells both drugs and tests, and certain countries (like the Netherlands) also have labs that test your drugs for a small fee with no chance of prosecution. Alternatively in the Netherlands you can also buy the tests from normal webshops like https://azarius.nl/.

[jborden13]

1P-LSD is a "research chemical" that is not scheduled and available for purchase over the clearnet. You just have to promise not to allow humans to consume it. Apparently its effects are indistinguishable from LSD-25 (traditional LSD).

[dovdovdov]

I mean, having science as an excuse to do LSD is a win already.

[biofox]

Having previously volunteered for an LSD study, it probably isn't as much fun as it sounds. The study I was on was conducted on a cold hospital ward with bright fluorescent lights, and required having vital signs measured throughout -- not an ideal environment to trip in. One participant in my group stood up and walked out mid-briefing. Thankfully I wasn't chosen, though everyone there looked terrified.

The research and campaigning done by the Beckley Foundation [1] and MAPS [2] is absolutely fantastic though, and I encourage everyone to check out their work.

[1] http://beckleyfoundation.org/ [2] http://www.maps.org/