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Wow. Cool. I wonder how hard are the synthesises of the useful antidepressants like mirtazapine.

Also, I found ASX-05 (Phase III) uses a DM metabolite that is retained much more by the addition of brupropion. DM is the stuff in some cough syrups.

discuss

nv-vn|8 years ago

Well, mirtazapine isn't scheduled in the US so you can probably get some precursors with relative ease. You can find the synthesis info online [1] and at least some of the chemicals used in the synthesis are available online [2], though for the price it seems like it might be more economically feasible to just buy a pill from a pharma company.

[1] http://www.arkat-usa.org/get-file/22868/ [2] http://www.sigmaaldrich.com/catalog/product/aldrich/648434?l...