[bluetech]

Have you heard of persistence hunting? Here's is a short documentary from the BBC: https://www.youtube.com/watch?v=826HMLoiE_o

It is believed to be one of the oldest hunting techniques, and so would indicate that humans are in fact meant to run long distances. According to Wikepedia, the runner runs for "about two to five hours over 25 to 35 km (16 to 22 mi)".

[macspoofing]

The fact that the rest of humanity didn't bother with persistence hunting may also be a clue that we weren't designed for that either.

[adrianN]

Or it's a clue that we figured out that building a trap or using a weapon to kill an animal from greater distance burns a lot less calories.