> In multiple lineages, the substitutions A119S and A119N preceded substitutions to 111 and 122 (Hemiptera, Hymenoptera, Diptera). In Drosophila, where we have the greatest phylogenetic resolution, A119S was established before substitutions to sites 111 and 122 in the evolutionary lineage leading to D. subobscura, which appears to be polymorphic with respect to CG-insensitivity.
That is a hypothetical used to promote a narrative, all the test & observations presented show all mutations must be present for specialization. The Monarch only feeds on milkweed, but somehow it survived the A119s phase feeding on milkweed plant (CG-containing plant)without the needed 111& 122 mutation?
In an hypothetical adaptive walk. A119S does NOT provide sufficient CG-insensitivity so an insect with just A119S will die specializing in CG. The are other mutations needed for survival.
Moreover u left out:
“A119S is a common substitution among taxa that do not specialize on CG-containing hostplants“
Natural selection is undefeated.
Therefore the need for immediate substitutions to sites 111 & 122 in order to specialize on “CG-containing hostplants“
An adaptive walk has to show adaptation in the environment. If all the mutations occur outside the natural environment, without natural selection, it is not an adaptive walk.
ceejayoz|6 years ago
> In multiple lineages, the substitutions A119S and A119N preceded substitutions to 111 and 122 (Hemiptera, Hymenoptera, Diptera). In Drosophila, where we have the greatest phylogenetic resolution, A119S was established before substitutions to sites 111 and 122 in the evolutionary lineage leading to D. subobscura, which appears to be polymorphic with respect to CG-insensitivity.
inkaudio|6 years ago
In an hypothetical adaptive walk. A119S does NOT provide sufficient CG-insensitivity so an insect with just A119S will die specializing in CG. The are other mutations needed for survival.
Moreover u left out: “A119S is a common substitution among taxa that do not specialize on CG-containing hostplants“
Natural selection is undefeated. Therefore the need for immediate substitutions to sites 111 & 122 in order to specialize on “CG-containing hostplants“
An adaptive walk has to show adaptation in the environment. If all the mutations occur outside the natural environment, without natural selection, it is not an adaptive walk.