[Bartweiss]

This is a novel and important result in antibiotics. It's also a proof-of-concept for using ML to produce vital drugs with novel mechanisms, rather than incidental alterations or discoveries in noncompetitive spaces. It might be an incremental speedup or computing-power advance in ML drug discovery also, but it could equally just be the result of a lucky break or a particularly large lab-test budget. (In which case, "why didn't someone do it already?" is closer to asking why nobody else bothered to win the lottery.)

It's not a major theoretical advance in ML drug-discovery techniques or the first big step in ML drug discovery. It's certainly not the invention of ML drug discovery or neural nets as an ML technique, both things I've seen implied in news stories on this work.

This is attention-worthy, absolutely. (I'll leave "publication-worthy methodology" to experts.) But it's newsworthy on actual merits, as a drug breakthrough and a demonstration of an increasingly-important technique. So I share the frustration when lazy or confused reporting implies this is the same style of ML-theory breakthrough as CNNs, Transformers, or even neural nets themselves.