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heurifk | 5 years ago

Normal cells also use RNA during protein synthesis. Why doesn't remdesivir disrupt that too and kills healthy cells?

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est31|5 years ago

There is no RNA cloning machinery in our cells. The RNA is instead copied from the DNA in the nucleus. Viruses like the coronavirus actually bring their own RNA cloning machinery that's assembled by the cell. Remdesivir only blocks the RNA cloning proteins of the virus.

rocqua|5 years ago

Doesn't that mean that Remdesivir would essentially defeat _all_ RNA viruses? Or is the effectiveness dependent on the exact RNA cloning mechanism used by the virus?