Very cool. I do wonder if it means a guaranteed wipeout of the gut microbiome though. Granted, this is likely to be a last line of defense, but _C. diff_ is nothing to mess with either. Sure, we'll be able to kill that with this too, even the nasty vancomycin-resistant strain, but too long with an empty gut isn't good for us either. We'll probably need to get better at microbiome engineering and probiotic used to compensate.
Well, antibiotic use is associated with diarrhoea and increased risk of C. difficile infections for this very reason. But the gut eventually gets recolonised by commensal bacteria - either from food or from the appendix[0]. In the worst case, we could always resort to probiotics or fecal transplants.
[+] [-] icodestuff|5 years ago|reply
[+] [-] uj8efdkjfdshf|5 years ago|reply
[0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551545/