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Munky-Necan | 5 years ago

Culture negative pneumonia is a relatively common phenomena. It's also quite difficult to get adequate sputum cultures, but in this case where n=60 I'm skeptical that was the issue. There could be a lot of potential causes for this, but COVID is low on the differential.

I want to say that spillover events, or a virus jumping from X host to humans, happens all the time. COVID became a pandemic because human to human transmission was possible from genetic mutation. Usually with spillover events humans are a dead end host and the person infected will be an n=1.

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arkades|5 years ago

> It's also quite difficult to get adequate sputum cultures

Heck yes. PNA cx will come back negative a good 2/3 of the time. Doesn't mean an awful lot.