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morraa | 5 years ago
And you make a great point. We've been constantly reminded that virtual spaces created by CROs are not always executable. As such we can actually constrain our algorithms to require very high probability of reaction success to remove false positives. We then tell the CRO what building blocks they need and the route design. We're still figuring how much of the lifecycle of making molecules is worth going after or, if indeed as you say, the route itself is the key solution.
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