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iridium_core | 5 years ago

Is there any evidence that this new 'variant' has any impact to infectiousness or death?

Or is it simply genetic drift?

discuss

order

maxerickson|5 years ago

What does 'evidence' mean in the question?

There is certainly something going on in the UK and Ireland, but it's not a randomized controlled study designed to measure the infectiousness of the variants that have recently been sampled there.

(because it's exponential, higher infectiousness can be quite a lot worse than higher lethality)

avl999|5 years ago

No evidence that it is deadlier than other variants. Some evidence that it is more infectious.

fpgaminer|5 years ago

It should be noted that increased infectiousness will inherently result in a larger number of deaths, even if it is not "deadlier". i.e. the new strain may still only be fatal in 0.5% of cases, but if it infects more people that's more rolls of the dice. The original strain was only projected to infect 60-70% of the population (if left unchecked). A new strain being 70% more infectious drastically changes that figure.

Not to mention a similar uptick in serious cases and even just more people presenting to the hospital. Imagine the current situation, where some cities are already at 0% capacity, but 70% worse...

Just something worth noting when we say that a new strain is _just_ more infectious.

sbinthree|5 years ago

It's been rapidly becoming the dominant variant in places with various different kinds of measures so I think it's for sure more infectious at this point.

JamesBarney|5 years ago

Just a reminder that greater infectiousness is worse than greater lethality.

Say you have two variants, variant S-spreader and variant L-lethal. S kills 1 in 100 people and has a doubling time of 3.5 days L kills 2 in 100 people and has a doubling time of a week.

First week L kills twice as many people of S. Week 2 they kill the same number of people. Week 3 S kills twice as many people as L Week 4 S kills 4x as many people as L.

graeme|5 years ago

Yes. Denmark has studied it and the new variant is doubling its prevalence in denmark every week too.