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samchorlton | 5 years ago

Exactly. Better analytics can enable this technology to produce better results than competing technologies in less time. Once automated/easy/rapid sample prep comes, there will be mass adoption in the space.

Disclaimer: Co-Founder of BugSeq[0] 0: https://bugseq.com

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matthew_stone|5 years ago

> Once automated/easy/rapid sample prep comes, there will be mass adoption in the space.

Sounds like Elon calling biology a “software problem”.

Not saying that you’re wrong, just saying that the computational folk tend to discount the challenges and skills required in the wet lab.

samchorlton|5 years ago

Agreed - Definitely a different class of problem than "software". There are large barriers, eg. lab contamination, biocontainment, low input protocols, etc; however, technological innovation will help with these.

That being said, we see a future where someone without advanced molecular training can put a sample (whether that's a nasal swab, concerning white powder received in the mail or lab-grown meat) in a black box and get out a meaningful report.

phkahler|5 years ago

>> Not saying that you’re wrong, just saying that the computational folk tend to discount the challenges and skills required in the wet lab.

It's time to bring in the industrial automation folks. They probably won't invent a fancy new algorithm to reduce the time to splice the pieces together, but they'll fine tune and automate your reader to the 9's.

koeng|5 years ago

Yea automated sample preps are key for me. The main thing that is overlooked in synthetic biology about nanopore is it has the capability to dramatically lower cost of indexing, which turns out to be one of the main prohibiting costs for dropping the cost of plasmid production.