I've seen the best results with Tribal Fusion and Casale Media. Unless you're in a high-premium field, don't expect more than $2 EPM for a 300x250 (or equivalent area) spot.
ValueClick Media and Burst Media are a couple of other top tier ad networks to look into. Google AdSense is obviously another option worth considering.
Depending on your niche and traffic though you may be better either directly selling to advertisers (serving/tracking ads through OpenX, Google DFP, or OIO Publisher is pretty straight forward).
Again depending on your niche you might find a vertical ad network - there are these for food, health, religion, music, sport and pretty much any other popular vertical you can think of. They tend to get better ads at better rates - but obviously have higher entry requirements.
primitive|14 years ago
I did a short write up of using the major players over at http://www.adbalance.com/ad-networks/
Depending on your niche and traffic though you may be better either directly selling to advertisers (serving/tracking ads through OpenX, Google DFP, or OIO Publisher is pretty straight forward).
Again depending on your niche you might find a vertical ad network - there are these for food, health, religion, music, sport and pretty much any other popular vertical you can think of. They tend to get better ads at better rates - but obviously have higher entry requirements.