[batterseapower]

This very cool article explains the mRNA sequence chunk-by-chunk which might give you a flavour of why differences exist: https://berthub.eu/articles/posts/reverse-engineering-source...

[type_enthusiast]

That is a super interesting article, thank you for posting it!

But, I guess my question is more about why the abstraction of "protein chunks" doesn't fall apart when there are relatively significant "diffs" in the RNA sequence.

[flobosg]

The most significant diffs between both vaccines occur in the untranslated regions located around the protein coding sequence and will never be present in the actual spike protein.

Regarding the protein coding region, because of the degeneracy/redundancy of the genetic code, all changes within it are synonymous and code for identical amino acids.

[zbirkenbuel]

That is a fascinating read (and the perfect level of depth in this field for me). How did you happen across it? Always looking to add a good source to my RSS feed list

[boruto]

dont know about op, but the link is present in the posted git repo readme.

[Ericson2314]

> Our body runs a powerful antivirus system (“the original one”).

Awwww