top | item 27301993

(no title)

axiak | 4 years ago

this paper is discussing mechanisms limited to the J&J and Astrazeneca vaccines

discuss

order

giantg2|4 years ago

Are the mechanisms limited to those, or did they only investigate the proteins specific to those vaccines? My understanding is that they only looked at the spike proteins for those vaccines and did not evaluate the others. My understanding is that the proteins in the others have the potential to interact similarly with the ACE2 mechanism but were not evaluated.

ericbarrett|4 years ago

The issue seems to be with the DNA -> mRNA transcription required by the adenovirus vector of the J&J and AstraZeneca vaccines, leading to mutated spike proteins which can cause clots. The Pfizer/Moderna shots don't use this mechanism so weren't the subject of the paper.

(This is not my specialty at all, just summarizing the abstract & what other commenters wrote since nobody replied to you yet)

I'm sorry about your father-in-law.