PathWhiz is pretty general (https://smpdb.ca/pathwhiz) and covers most of that. Give it a go! You can sign in as a guest and start creating pathways. All of the gene information is included and pulled in from Uniprot as well as a bunch of other sources. Small molecule data is integrated with HMDB, DrugBank, and a bunch of other sources as well. (disclaimer: although I didn't work on this tool, I worked on the first version of SMDPB).
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