[dboshardy]

Yes, it will evolve further, but human ACE2 receptors aren't evolving rapidly within a generation any time soon. There's a metaphorical window of possible mutations that will allow SARSCov2 to bind to receptors and a huge swath of that window clearly is taken up by protection from vaccines (especially mRNA ones). There is a finite space in which it could still evolve _and_ evade vaccines. That space is likely _extremely_ small. "Too much" evolution renders it ineffective at infecting humans.

[mikepurvis]

Do you have a reputable source which elaborates further on this discussion? My impression thus far is that few are willing to assert with the confidence you're displaying here that we're out of the woods once vaccinated.

Indeed, Pfizer has announced that it is working on a booster that specifically targets Delta, so that says to me that there is very much still a concern here:

https://www.cnbc.com/2021/07/08/pfizer-says-it-is-developing...