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reader_mode | 4 years ago

>This isn't a meaningful claim for 2 key reasons. There has never been a vaccine that had serious side effects that did show up shortly after vaccination[2]. The history of mRNA treatments began as an experiment in gene therapy, but has largely ben abandoned because the effects never lasted long enough. As of 2020 this is an ongoing area of research[3]. No one has figure out how to stabilize mRNA so that it has long lasting effects.

This isn't really what I'm worried about. Right now people are talking long COVID, subtle long term brain damage and it seems like mechanisms are still unknown. So who's to say that immune system reaction triggered by vaccination isn't causing same kind of hard to detect damage. I'd be much more comfortable with the vaccine if the long COVID studies included groups :

- no vaccination/hospitalised

- no vaccination/asymptomatic

- vaccination/not infected

- vaccination/infected

I'm not a risk group and have no problems with social distancing so I'm waiting for stuff like this to come out.

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titzer|4 years ago

> I'm not a risk group and have no problems with social distancing so I'm waiting for stuff like this to come out.

Respectfully, I think what you're really waiting for is this thing to blow over so you don't have to take any personal risk. That's likely to be a fail, as you're just a waiting Petri dish for the live virus to infect.

All kinds of things have risk and the craven merchants of doubt are busy spreading FUD about the vaccine. It's really our only way out of this shit show, because waiting around is just prolonging it.

Or would you like to have a long drawn out conversation about the long term health effects of:

* preservatives

* artificial sweeteners

* high fructose corn syrup

* pesticides

* HPV infection

* influenza/rhinovirus infection

* sunburns

* a night of heavy drinking

Because we can absolutely have a long, drawn out, twisting conversation about all those things.

reader_mode|4 years ago

On one hand I'm being presented with avoiding long COVID sideffects as a reason to get vaccinated - on the other I get no proof that vaccination doesn't do similar harm and that it's actually protective of those effects.

I don't really mind social distancing measures untill people in the risk groups get vaccinated - all of my high risk contacts have been. So I don't get what we need to get out of, my government is already saying they will eliminate COVID measures after summer, UK style.

I'll get vaccinated at some point if I have to do it for travel or what not - right now I'm not convinced - the social arguments don't make much sense to me (variants will come up anyway, you can get infected and spread the virus even if vaccinated you're just reducing risk)

ch4s3|4 years ago

> So who's to say that immune system reaction triggered by vaccination isn't causing same kind of hard to detect damage

This is pure conjecture base on literally nothing. I don't mean to sound harsh, but it's just baseless. The immune response from the vaccine works like any other type of vaccine immune response. The mRNA vaccines cause you own cells machinery to build virus proteins at which point it works just like any viral subunit vaccine, which have existed since 1970 and include flu vaccines, hep A and B, and few other you may have had already. Billions of people have received those types of vaccines and they don't have long term negative effects, except rarely when someone has an acute reaction right after vaccination. It is true that some people have allergic reactions (a strong an destructive immune response), but they happen within about 4 hours and symptoms usually clear up in a few days.

If the COVID vaccines had some mysterious far off long term effects, it would be the first vaccine ever to do that, and there's no reason to suspect that might be the case. You may find this nature article interesting https://www.nature.com/articles/s41577-020-00479-7, it's about general vaccine immunology.

I'm not telling you that you need to get vaccinated, but the particular concern you're raising isn't something you should be worried about.

reader_mode|4 years ago

>The immune response from the vaccine works like any other type of vaccine immune response.

You are assuming because the mechanism is the same that the effects will be as well - it's like saying "we have this black box service we sort of have an idea of what it does and if we send it X/Y/Z we know what happens, it should work the same with W too - I've been in that scenario often enough to know that's an assumption that I'd rather see the data for.

I already saw that people in my peer group reported short term side effects like headache after getting vaccination, have taken days off from work, family members complained about dizziness the day after.

It's relatively easy to do these studies along with long COVID studies, should be insignificant even compares to money that will be spent on vaccination campaigns - so why skip out on valuable data.