Maybe it is working, but being coerced to take a novel gene therapy from organizations with a long history of abuse is a horrific precedent that should offend everyone.
I assume you are referring to mRNA vaccines here. These are not in any way "gene therapy." Please quit spouting misinformation.
For reference:
> Gene therapy is a medical field which focuses on the genetic modification of cells to produce a therapeutic effect[1] or the treatment of disease by repairing or reconstructing defective genetic material.[2]
First: Injecting RNA into cells that currently have reverse-transcriptase proteins active? I'm afraid it will modify DNA. So in any cell currently infected with a retrovirus, and there will be a lot of those in any human, it will modify DNA.
Of course, no more (in fact significantly less) than the virus will. But mRNA vaccines, when used against a retrovirus, will modify DNA.
Second: it would be considered Gene therapy whether or not it modifies DNA.
Thirdly: all RNA activity will result in expression changes for other Genes. That might not modify the DNA directly, but most researchers now consider that part of the genetic material of the cell. Again, probably a lot less than a virus would.
Fourthly: all "negative" (meaning it cuts out "wrong" DNA rather than adding some) gene therapy treatments only inject RNA as well. It's not quite the same as an RNA-based vaccine.
actually_a_dog|4 years ago
For reference:
> Gene therapy is a medical field which focuses on the genetic modification of cells to produce a therapeutic effect[1] or the treatment of disease by repairing or reconstructing defective genetic material.[2]
https://en.wikipedia.org/wiki/Gene_therapy
mRNA vaccines do not modify cells, repair, or reconstruct anything.
candiodari|4 years ago
Of course, no more (in fact significantly less) than the virus will. But mRNA vaccines, when used against a retrovirus, will modify DNA.
Second: it would be considered Gene therapy whether or not it modifies DNA.
Thirdly: all RNA activity will result in expression changes for other Genes. That might not modify the DNA directly, but most researchers now consider that part of the genetic material of the cell. Again, probably a lot less than a virus would.
Fourthly: all "negative" (meaning it cuts out "wrong" DNA rather than adding some) gene therapy treatments only inject RNA as well. It's not quite the same as an RNA-based vaccine.
kook_throwaway|4 years ago
>Please quit spouting misinformation.
I like how you start with the word "please" so you can pretend you're being polite.
[1] https://www.sec.gov/Archives/edgar/data/1682852/000168285220...