[arshajii]

Hi everyone, I’m one of the developers on the Seq project — I was delighted to see it posted here! We started this project with a focus on bioinformatics, but since then we’ve added a lot of language features/libraries that have closed the gap with Python by a decent margin, and Seq today can be useful in other areas or even for general Python programs (although there are still limitations of course). We’re in the process of creating an extensible / plugin-able Python compiler based on Seq that allow for other domain-extensions. The upcoming release also has some neat features like OpenMP integration (e.g. “@par(num_threads=10) for i in range(N): …” will run the loop with 10 threads). Happy to answer any questions!

[adgjlsfhk1]

Have follow-up benchmarks vs BioJulia been done since 2019? If I remember correctly at the time, the result was that BioJulia was faster once you consider that it did validation.

[arshajii]

We haven't done too many comparisons with BioJulia since that paper, although we did address the (valid) issues they raised such as data validation (i.e. Seq now validates input data by default, but this can be optionally disabled). We did compare against them in our last paper in a sequence alignment benchmark: https://www.nature.com/articles/s41587-021-00985-6 (check the supplement).