[Saptarishi]

I think the point is, the memory cells do not retain this knowledge for extended periods of time in the case of the current Covid vaccines we have. So should we be looking for a 3rd dose, or try to fund a different vaccine?

[rob74]

Well, that's the question that this study doesn't answer. They (of course) didn't try to infect seniors with reduced antibody response with Covid, they only studied the antibody response in the lab. So the memory cells probably weren't a factor in the lab tests...

[LurkingPenguin]

> I think the point is, the memory cells do not retain this knowledge for extended periods of time in the case of the current Covid vaccines we have.

I didn't see any mention in the article about memory T and B cells. The article only mentions antibodies. Where did you see this?

[Saptarishi]

Antibody remembrance comes from memory cells isnt it? I may be wrong.

[GeekyBear]

The people who had the original version of SARS 20 years ago, still have an immune response today. Memory cells work just fine.

https://www.nature.com/articles/d41586-021-02260-9

When you encounter the virus again, those with a healthy immune system will ramp up antibody production.

[kjaftaedi]

>the memory cells do not retain this knowledge for extended periods of time in the case of the current Covid vaccines we have

This is a very misinformed statement as this data hasn't been collected yet.