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Ginkgo Bioworks (YC S14) is going public today

151 points| todsacerdoti | 4 years ago |blog.ycombinator.com | reply

66 comments

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[+] tito|4 years ago|reply
If anyone will enable the world to engineer biology, it's Gingko.

Their team has built a platform for biological engineering since day 1.

This is the summary:

* platform for engineering biology (unfair advantage is they've taken this "not a product company" approach since 2009)

* investing up the ecosystem by taking upside in products they engineer for larger companies (not sure if they have an unfair advantage here besides creative financing and momentum, IPO helps with that)

* investing downstream into startups by providing their platform in exchange for equity (YCbio partnership seems like an unfair advantage here)

* mindshare of new minds (iGEM itself is a breeding ground for future synbio employees and leaders who dream of joining Ginkgo, Ginkgo founders co-created iGEM)

Pretty perfect flywheel right there, even if it risks being a spaghetti monster from a corporate structure and cashflow standpoint.

So cool to see this finally coming to light as an IPO. While I don't understand the SPAC benefits, Ginkgo's structure to be able to invest resources into synbio startups in an equity exchange sets them up really well for future cashflow even if the present is not.

(Disclosure Ginkgo bought lab equipment from me in the early days, and I just bought their stock today) https://www.ginkgobioworks.com/2009/09/01/pearl-biotech-open...

[+] neural_thing|4 years ago|reply
I sold my Ginkgo today. I like the company but... Most of their revenue is stock in affiliated companies. I don't think they have a real business today, and the valuation is insane.

Amyris actually has a synthetic biology business. It's less flashy but it's real.

[+] fouc|4 years ago|reply
synbio.. wow, talk about flashbacks to genetic hacking cyber punk scifi
[+] kilroy123|4 years ago|reply
I'm currently looking seriously at creating a synthetic biology software startup. Like a poor mans ginkgo.

These guys are MASSIVE in the space. Think Google back in the day.

I predict this will be a hot stock.

Edit: if you're also interested in starting synthetic biology startup please get in touch.

[+] koeng|4 years ago|reply
I’m a major contributor to a synbio software package https://github.com/TimothyStiles/poly and I also do quite a lot of robotics in the space (have a full DNA foundry running in my house, that took a lot of software).

Already starting something in the space, but I’d be happy to talk!

[+] cinntaile|4 years ago|reply
At this point they're massively overvalued if you ask me, that seems to be the case for every synthetic biology company but this one takes the cake.
[+] cybernautique|4 years ago|reply
I'm interested, but in the it's-something-I-aspire-to-some-day-when-I'm-not-so-incompetent sense. However! I'd love to engage with you to hear about what's up! Is your inbox open to general curiosity, or would you rather keep emails limited to serious takers currently?
[+] hsuduebc2|4 years ago|reply
Sounds interesting. Maybe this question would sound weird but how do you get an idea for a product? I mean in synth biology. Like. I think that I can produce this chemical with bacteria more simply/cheaply?
[+] refurb|4 years ago|reply
As someone who works in the biotech space it’s still fuzzy to me what Gingko offers. Looking at their pitch deck I see partnerships with milestone payments across multiple industries agriculture, chemicals, bio security and now pharmaceuticals.

Does Gingko have a proprietary technology to offer or are they just a centralized platform?

I did notice their latest focus is pharmaceuticals where the huge margins are, but most biotechs will treat manufacturing as a patented process. So with Gingko just take royalties? If so there are plenty of other biotechs (probably many no one has heard of) that do this very successfully.

The business model is still not clear.

[+] john_yaya|4 years ago|reply
I would say they’re following Zymergen’s business model… except that model turned out to be “defrauding the investors.”
[+] jc_811|4 years ago|reply
I noticed they went public via SPAC, which, as an investor, screams red flag and scares me.

Can anyone shed light on why they would go this route? Is it accurate to say best case is because they wanted less hassle / quicker to market and worst case is that their financials/books are a disaster and they didn’t want anyone looking too closely before the founders raised money and cashed out?

Genuinely curious and would appreciate any insightful replies

[+] neural_thing|4 years ago|reply
Most of the answers here are wrong. The real reason is that when companies go public through a regular IPO, they can't show projected financials, only actual results.

Ginkgo has poor results so far, but huge projections, which a fair number of people believe. So, SPAC.

[+] kharak|4 years ago|reply
I don't really understand SPACs. Is there a good article explaining what they do and why you take them instead of going public directly. And what happens to those SPAC shares now if you bought some?
[+] jy1|4 years ago|reply
Regular bankers dont want to IPO hard tech companies. SPACs are great for hard tech with future revenues.
[+] gingkoguy|4 years ago|reply
They are a great company and could have gone traditional IPO. However, with going SPAC they were able to bring 2 billion dollars into a company with super high valuation. They make less than 50mil and we’re valued at 18 to 20 billion. So don’t buy in now, you will have plenty of chance to buy this great company

Edit: Also just to add on by bringing in that 2 Billion dollars they have essentially secured the future of the company for a long time

[+] irq-1|4 years ago|reply
That does seem bad.

https://www.sec.gov/oiea/investor-alerts-and-bulletins/what-...

> If you invest in a SPAC at the IPO stage, you are relying on the management team that formed the SPAC, often referred to as the sponsor(s), as the SPAC looks to acquire or combine with an operating company. That acquisition or combination is known as the initial business combination. A SPAC may identify in its IPO prospectus a specific industry or business that it will target as it seeks to combine with an operating company, but it is not obligated to pursue a target in the identified industry.

[+] bpodgursky|4 years ago|reply
SPACs are a great way to not have to hemorrhage IPO money to wall street bank cartels, and to lose billions w/ undervalued IPOs. I'm not sure what you're on about.
[+] murgindrag|4 years ago|reply
Serious question: How does YC work with companies like this?

It seems like a YC standard-form offer doesn't make any sense to a company like Ginko at the stage it entered YC.

[+] lr|4 years ago|reply
Robinhood currently has the Genentech description attached to Ginko Bioworks (DNA)!
[+] ArtWomb|4 years ago|reply
Congrats! Great to see this from inception in 2014 to news recently that they work with Moderna to scale synthetic DNA vaccine production to global demand. I like Part Deux of their revenue stream: royalties. Taking equity stakes in spin off bio-engineered consumer products. And the best part for a biotech startup, faster regulatory approval than pharma ;)