[CryoLogic]

The active dose to LD50 ratio for alcohol is somewhere about 1:13 depending on tolerance. For Magic Mushrooms or LSD, it is above 1:1000.

In other words, it is nearly impossible to accidentally kill yourself via overdose on psychedelics - but somewhat easy with alcohol.

https://en.wikipedia.org/wiki/Median_lethal_dose

[sharkweek]

But it sure is a hell of a lot easier THINKING you’re going to die while on psychedelics!

I can’t handle drugs (as much as I’m curious about them) but I had a “smoked waaaay too much pot”experience in college where I was high for almost 24 hours and I spent the first six hours or so convinced I had broken my brain and was going to die.

[bagacrap]

I think you have to balance that against the fact that the recreational dose of lsd is so infinitesimal that 10000x that dose is still very easy to ingest in the blink of an eye. Not so for alcohol.

That said, even after reading wikipedia's source on the ld50 of lsd, I remain unconvinced that there even is a lethal dose of LSD.

[IIAOPSW]

An excerpt from the highest ever recorded dosage of LSD.

"Eight individuals who accidentally consumed a very high dose of LSD intranasally (mistaking it for cocaine) had plasma levels of 1000–7000 μg per 100mL blood plasma and suffered from comatose states, hyperthermia, vomiting, light gastric bleeding, and respiratory problems. However, all survived with hospital treatment and without residual effects."

https://maps.org/research-archive/w3pb/2008/2008_Passie_2306...

In short, even on the rare occasion when people have taken 1000x what they should, they didn't die.

[nitrogen]

There are other forms of danger apart from lethality, and before new recreational (or therapeutic) drugs can be accepted by society, those need to be culturally understood.

[agumonkey]

You don't need to somatically die. If you end up mentally borked that is enough.