[didjathinkmess]

Natural immunity followed by a single dose is the strongest immunity available supposedly. Many of us likely have cross reactive immunity from a previous Coronavirus infection from before the pandemic.

Regarding "better antibodies", that doesn't make any sense to me. More in number perhaps, but better? It's the exact same formula being given as boosters.

[astrange]

Omicron does escape natural immunity + no booster though.

https://www.tandfonline.com/doi/full/10.1080/22221751.2021.2...

Similarly, immunity to omicron might not be good at the other variants (which are worse for you), which is why reusing the existing boosters instead of making new ones isn't that bad an idea.

[logic_beats_pro]

I think your first sentence is a bit premature considering the study. Its forgivable to post this because it's so early but seriously, this was done in test tubes.

"One major caveat of the current study is that we used an in vitro assay system and the pseudotyped viruses but not the real viruses were used in the assay."

[Volundr]

We train neural nets on the same training sets for multiple iterations and expect it to come up with new/better connections. When learning a new skill we may meditate on previously solved problems and discover better solutions. Why would the immune system not have the capability to continue experimenting and learning from the same stimulus?