Will this be a neutralizing vaccine? I like the idea of mRNA based vaccines but unless it prevents infections and is permanent like for polio, I don’t see any great uptake if it’s expected to decompose rapidly like the COVID vaccines.
The inactivated polio vaccine used in the US doesn't elicit neutralizing antibodies, just binding ones. The oral polio vaccine used abroad can elicit neutralizing antibodies, but also sometimes gives recipients polio. There are always tradeoffs...
Ideally we’d want neutralizing vaccines wouldn’t we? Before the pandemic, my idea of a vaccine was a preventative measure that worked for long periods of time. I read Harvard did a study of tetanus shots and found boosters had no significant statistically beneficial effect.
I have never heard of a polio vaccine have this issue, I think Salk did an excellent job at testing it’s effects without forcing participants and there’s a great deal of historical data to prove it. Of course a vocal minority may have issues but I haven’t heard them on polio at all, only on relativity new Lyme disease vaccine ‘causing autism’.
I’ll look at binding vaccines more, I just want vaccines that aren’t subscription services.
What would a neutralizing vaccine against ticks look like? And why would it matter that much for a parasite that doesn't usually go from human to human?
The polio vaccination is 4 doses, and a booster every 10 years if you are at risk. Maybe the covid vaccines will fare similarly. Two shots very close to each other isn't ideal for immunisation, we knew that from the beginning.
It would cause tick saliva from causing infection for a lifetime, it matters so you can give a vaccine and not need to upkeep it especially in rural areas. It matters because it will prevent it forever. I think I’m thinking of something that lasts longer, someone mentioned a binding vaccine.
What does at risk of polio mean? I read that polio infections only affect Americans who aren’t vaccinated and touch recently vaccinated baby feces. If you aren’t in that situation you won’t get polio.
apendleton|4 years ago
GhettoComputers|4 years ago
I have never heard of a polio vaccine have this issue, I think Salk did an excellent job at testing it’s effects without forcing participants and there’s a great deal of historical data to prove it. Of course a vocal minority may have issues but I haven’t heard them on polio at all, only on relativity new Lyme disease vaccine ‘causing autism’.
I’ll look at binding vaccines more, I just want vaccines that aren’t subscription services.
CorrectHorseBat|4 years ago
The polio vaccination is 4 doses, and a booster every 10 years if you are at risk. Maybe the covid vaccines will fare similarly. Two shots very close to each other isn't ideal for immunisation, we knew that from the beginning.
GhettoComputers|4 years ago
What does at risk of polio mean? I read that polio infections only affect Americans who aren’t vaccinated and touch recently vaccinated baby feces. If you aren’t in that situation you won’t get polio.