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georgekv | 4 years ago

The biggest reason the under 5s vaccine is taking so long is that they don't suffer severe enough symptoms that they can easily test the efficacy of the virus. The same issue was there with the 5-11s but pharma, CDC, & FDA just glossed over that to approve the vaccines.

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beerandt|4 years ago

>The biggest reason the under 5s vaccine is taking so long is that they don't suffer severe enough symptoms that they can easily test the efficacy of the virus.

How does anyone convince themselves that this is actually a problem?

Especially when the vaccine no longer prevents catching the virus or transmitting it.

What remaining benefit are people so eager to confer upon their toddlers?

chithanh|4 years ago

Vaccines still lower disease severity.

Also vaccines reduce risk of some post-acute COVID disorders like MIS-C (which can result even from asymptomatic COVID).

https://www.cdc.gov/mmwr/volumes/71/wr/mm7102e1.htm

And of course you don't want to infect your child with a disease that has long term consequences which we are still learning about. Diabetes hit the news recently in the US, but it is actually been known for a while in other countries.

https://www.cdc.gov/mmwr/volumes/71/wr/mm7102e2.htm

https://diabetesjournals.org/care/article/43/11/e170/35903/N... (UK)

https://adc.bmj.com/content/early/2021/05/27/archdischild-20... (Finland)

If that wasn't bad enough, diseases that are associated with T1D like celiac disease are on the rise, and show stronger association in COVID patients:

https://onlinelibrary.wiley.com/doi/10.1111/apa.16173

lttlrck|4 years ago

> Especially when the vaccine no longer prevents catching the virus or transmitting it.

The vaccines never stopped catching or transmission... they lessen the chances of you developing severe symptoms, your immune system still has to work.

notch656a|4 years ago

Well Virtue with a capital 'V' is one big one! And of course they're an excellent source of revenue for Pfizer et al. You wouldn't want to risk it would you?

-- writing this while my toddler is banished from daycare for 10 days because a single kid there tested positive.

s5300|4 years ago

Having your children’s lungs scarred to 20% function and not getting to realize it’s even happened until they start a sport or something doesn’t sound fun to me, perhaps that’s why.

throw6622|4 years ago

The success we’re talking about was an analytical measurement of the antigen response in the body. It wasn’t lack of symptoms which ruled that phase a failure.

Sparyjerry|4 years ago

That is incorrect, the decision making numbers used to test vaccine effectiveness having nothing to do with lab antigen numbers, they are based on how much symptomatic illness is avoided. All of the results such as as 95%-96% efficacy for Phizer and Moderna and 66% for J&J are based on the % reduction of symptomatic illness only. Not the reduction in actual illness or based on lab tests of antigen response.

dataflow|4 years ago

> that they can easily test the efficacy of the virus

I think you meant to type 'vaccine'

tablespoon|4 years ago

> The biggest reason the under 5s vaccine is taking so long is that they don't suffer severe enough symptoms that they can easily test the efficacy of the virus.

Do you have a source on that?

My understanding is the reason it's taking so long is 1) an abundance of caution because the risk/reward calculation is different and 2) young children's immune systems don't work the same as adults').

mritchie712|4 years ago

Do you have a source for this?