[podgaj]

Endocannabinoids have been known for a while, but how Endocannabinoids are made in the human body is a newer discovery (~2016).

What should be being broadcast is how important Omega 3 is for increasing CB1R and CB2R activity to reduce inflammation and disease. This has everything to do with COVID and learning to live with SARS2 without people dropping dead or having to stay home from work. This is something everyone can do now, without waiting for legalization, working about dosing, or giving money to yet another 3rd party.

Why is there so little talk about Omega 3 and lowering COVID complications?

Because people are trained by the media everyday that drugs are the answer to everything and diet does not matter.

The global cannabidiol market size was valued at $2.8 billion in 2020 and is expected to expand at a compound annual growth rate of 21.2% from 2021 to 2028. Do you think these people want you to know that the same anti-inflammatory action can be achieved by lowering Omega 6 and increasing Omega 3 in your diet?

[netizen-936824]

I'm not aware of any evidence that activity at CBR1 or 2 has any effect on the proliferation of SARS-CoV-2

The study at hand doesn't suggest a mechanism and most endogenous transmitters are extremely local. This means that they won't necessarily go where the virus is. Taking an exogenous drug allows for a greater degree of tissue distribution

On top of all that, the study also mentions this:

>The CBD metabolite 7-OH-CBD, but not a panel of closely related CBD congeners, exhibits antiviral activity

This makes me suspect that the mechanism of action is unique to CBD and would likely not be the same as the endogenous transmitters

[podgaj]

It’s about controlling the out of control inflammation caused by the body fighting the infection.

[loxias]

> how Endocannabinoids are made in the human body is a newer discovery (~2016).

HUH. TIL.

In my early 20s in the 2000s, among my stoner peers "isn't it neat how many fascinating compounds have endogenous counterparts! do you think we'll ever understand how they're made or how the body uses them?" was one of those "maybe we'll never know" sort of topics for discussion.

It's so cool to see science do the whole "first we don't know, then time passes, then we know" thing.