“Brave”? That talked about non clinical (in vitro) work. The only reason the drug was ever discussed is that it long previously (pre Covid) had shown antiviral behavior in vitro that did not appear in vivo. So this article merely reported an unsurprising result.
The appearance of effects in vitro that do not appear in vivo is unfortunately extremely common.
There are several studies showing positive effects of ivermectin in vivo. Here is one [0] two [1].
One potential problem with ivermectin is it's patent expired in 1996. So not a lot of money to be made from a generic treatment that is cheap and abundant.
How far would Big Pharma go to secure profits? [2] Find out for yourself. Warning ignorance really is bliss and your worldview may be shaken.
I've used a VPN to get the original PDF (reachable from Japan only) https://kowa.co.jp/news/2022/press220131.pdf
and below's the Google Translated version. They are running a clinical study based on a fact that non-clinical study shown antiviral effect.
Kowa Co., Ltd. (hereinafter referred to as "Kowa") is the investigational drug "Ivermectin" used in Phase III clinical trials (development code: K-237) for the treatment of new coronavirus (SARS-CoV-2) infections. From a joint research (non-clinical trial) with Kitasato University, it was confirmed that the Omicron strain has the same antiviral effect as the existing mutant strain (alpha beta gamma delta strain). I did. As announced in July 2021, Kowa directly from Professor Satoshi Omura, a special honorary professor at Kitasato University, who won the Nobel Prize in Physiology or Medicine, about conducting clinical trials of ivermectin as a therapeutic drug for new coronavirus infections. I received a request. New Co. He believes that it is the mission of the pharmaceutical company to contribute to the treatment of coronavirus infections and protect the health of the people, and clinical trials to confirm the efficacy and safety of ivermectin against new coronavirus infections. We are conducting a test. Ivermectin has been distributed by WHO to infected areas for over 30 years as a treatment for parasitic infections. Especially in some African countries, it has been confirmed to be safe enough for volunteers to distribute directly to people. In addition, ivermectin has been reported to have the effects of suppressing the invasion of SARS-CoV-2 into cells and inhibiting replication, and is expected to be applied as a therapeutic drug (tablet) for new coronavirus infections as drug repositioning. I am. In this clinical trial, the dosage and administration are different from those already approved for the treatment of parasitic infections, but the efficacy and safety are being confirmed in the clinical trial. Kowa will contribute to the treatment of new coronavirus infections by confirming the clinical effect of ivermectin on SARS-CoV-2 and providing it to the public as soon as possible. * Overseas, it was reported that patients use high-content ivermectin for animals, which is dangerous to humans, and harmful events occur. Kowa is the standard for conducting clinical trials of pharmaceuticals in humans. Ivermectin clinical trials are conducted in accordance with the strict standards set by GCP (Good Clinical Practice).
gumby|4 years ago
The appearance of effects in vitro that do not appear in vivo is unfortunately extremely common.
TrispusAttucks|4 years ago
One potential problem with ivermectin is it's patent expired in 1996. So not a lot of money to be made from a generic treatment that is cheap and abundant.
How far would Big Pharma go to secure profits? [2] Find out for yourself. Warning ignorance really is bliss and your worldview may be shaken.
[0] https://pubmed.ncbi.nlm.nih.gov/33592050/
[1] https://pubmed.ncbi.nlm.nih.gov/34466270/
[2] https://www.amazon.com/Real-Anthony-Fauci-Democracy-Children...
unknown|4 years ago
[deleted]
alea_iacta_est|4 years ago
sm4rk0|4 years ago
Kowa Co., Ltd. (hereinafter referred to as "Kowa") is the investigational drug "Ivermectin" used in Phase III clinical trials (development code: K-237) for the treatment of new coronavirus (SARS-CoV-2) infections. From a joint research (non-clinical trial) with Kitasato University, it was confirmed that the Omicron strain has the same antiviral effect as the existing mutant strain (alpha beta gamma delta strain). I did. As announced in July 2021, Kowa directly from Professor Satoshi Omura, a special honorary professor at Kitasato University, who won the Nobel Prize in Physiology or Medicine, about conducting clinical trials of ivermectin as a therapeutic drug for new coronavirus infections. I received a request. New Co. He believes that it is the mission of the pharmaceutical company to contribute to the treatment of coronavirus infections and protect the health of the people, and clinical trials to confirm the efficacy and safety of ivermectin against new coronavirus infections. We are conducting a test. Ivermectin has been distributed by WHO to infected areas for over 30 years as a treatment for parasitic infections. Especially in some African countries, it has been confirmed to be safe enough for volunteers to distribute directly to people. In addition, ivermectin has been reported to have the effects of suppressing the invasion of SARS-CoV-2 into cells and inhibiting replication, and is expected to be applied as a therapeutic drug (tablet) for new coronavirus infections as drug repositioning. I am. In this clinical trial, the dosage and administration are different from those already approved for the treatment of parasitic infections, but the efficacy and safety are being confirmed in the clinical trial. Kowa will contribute to the treatment of new coronavirus infections by confirming the clinical effect of ivermectin on SARS-CoV-2 and providing it to the public as soon as possible. * Overseas, it was reported that patients use high-content ivermectin for animals, which is dangerous to humans, and harmful events occur. Kowa is the standard for conducting clinical trials of pharmaceuticals in humans. Ivermectin clinical trials are conducted in accordance with the strict standards set by GCP (Good Clinical Practice).