[jeffxtreme]

Interesting side point though from https://www.mercurynews.com/2022/02/28/uc-berkeley-loses-cri...:

''' But over time, according to one expert, the patents may lose value due to continued innovations.

“By the time that large scale commercialization occurs, there will probably be supplemental or supplanting technologies,” according to the UC attorney, who asked that his name not be used. '''

So if mid and late-stage companies continue to innovate for e.g. the purpose of productionizing CRISPR, the effect of the original patent will lessen in value. A nice note that there continues to be an incentive for progress in this space.