[inter_netuser]

That’s been known for a long time, possibly centuries.

morphine was used to treat depression as late as last century, and probably remains a common folk remedy even today.

[bink]

Morphine has more effects than just killing pain, however. It also provides a euphoric feeling. It's more interesting if a drug that was until now only known for removing physical pain can also provide relief for social pain.

[goldenkey]

It only does for a brief honeymoon phase. Then it's mostly a pain killer (chronic pain sufferer.)

[colechristensen]

Well yes, there’s definitely a reason there are problems with opiate addictions.

A differentiation between legal and illegal drugs is the legal ones poison you before they make you feel particularly amazing, the illegal ones poison you after. Take way too much acetaminophen and you get liver failure before you feel euphoria.

There are arguments to be made that many illegal drugs are safer at effective doses but have risks of abuse not present in the drugs that poison you before abuse is fun.

[Terry_Roll]

Depending on "who" you listen to Wild Lettuce is either no good or its better than morphine without the addiction. https://en.wikipedia.org/wiki/Lactuca_virosa https://erowid.org/plants/lactuca/lactuca.shtml

https://en.wikipedia.org/wiki/Lactucarium#History

So with man made chemicals they tend to not break down as easily, you see this with man made pesticides like pyrethrin's yet the pyrethrin's in Chrysanthemum do break down easily, organophosphates (nerve agents at the right dose) are another group used to dip Sheep in, but might show up in trace amounts in lanolin based Vit D3 supplements.