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jonmc12 | 3 years ago

Omega-3 index is better correlated with overall health than O3/O6 ratio. Also, flaxseed is a source of ALAs whereas early all O3 health benefits come from DHA/EPA. A great source of info is Dr Rhonda Patrick's interviews w/ Dr Bill Harris. Here is a short clip - https://share.descript.com/view/2w6WidsYZlT

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hervature|3 years ago

Yes, I know, we can keep going down this rabbit hole. Turns out that a completely vegan diet, which has no DHA, is completely sufficient to sustain the body [1]. The human body is incredibly adaptive and increases its efficiency of converting ALA to DHA/EPA. This conversation I think will shake down how the heme iron/non-heme iron efficacy research. A study long ago showed that non-heme uptake was much poorer than heme iron and so the conclusion was something like "you need to eat 10x the non-heme iron" which has since become "conventional" wisdom. When you remove heme iron (stop eating meat), your body is able to absorb non-heme iron at the same rate. We call this a "smart drug" which changes uptake based on concentration levels. Basically, the study participants at the time ate so much meat that their iron levels were so high that non-heme iron is not processed.

Edit: The other thing I wanted to say is 1 tbsp of flaxseed has 2.4g of ALA and that the adequate intake of ALA is 1.6g and 0.3g of DHA/EPA. If we assume a 10% conversion rate for both (depends on many factors and a tad high), you get 0.24g of DHA/EPA. So, 2 tbsp of flaxseed and you're good. I put it in my smoothie in the morning.

[1] - https://pubmed.ncbi.nlm.nih.gov/16087975/

adrian_b|3 years ago

The study linked by you has shown that the concentrations in blood of DHA and EPA for vegans were less than half of those for omnivores.

Therefore this study is also one of the many which have shown that the human body has only a limited capacity of converting ALA into DHA and EPA, so that the nutritional supplements with DHA and EPA are beneficial for vegans (e.g. from oil of Schizochytrium, a non-plant non-animal unicellular living being, which is falsely named as "algae" by vendors, to sound more like a vegetable to vegan ears, if the cheaper fish oil is deemed to be unacceptable).

This study certainly does not support your claim that "a completely vegan diet, which has no DHA, is completely sufficient to sustain the body".

Yes, it is enough to have ALA in your food to avoid a quick death, but ALA is not enough to ensure a good health and a long life.

BlargMcLarg|3 years ago

>The human body is incredibly adaptive

They say this and then don't address the elephant in the room: the huge fall-out rate concerning vegans going ex-vegan.

Additionally, "completely sufficient to sustain the body" is about the lowest barrier to entry one can set. People aren't interested in sustenance alone, even if you take away cultural factors.

hosh|3 years ago

You can get DHA from algea sources and still eat vegan.

There is also a sex-linked difference between ALA conversion to DHA/EPA, with women, and women who are pregnant or brestfeeding converting significantly more ALA to DHA than men. Men were converting far less than 10% while women were converting more than 10%.

raspberry1337|3 years ago

>" Turns out that a completely vegan diet, which has no DHA, is completely sufficient to sustain the body [1]. "

Massive claim with only one little study for a source. You are behaving like the strawman vegan right now, making ludicrous claims on nitpicked data; you are not furthering your cause by spreading disinformation online.

strken|3 years ago

ALA is metabolised to EPA and DHA, albeit in a pretty lossy way. Is there some reason it wouldn't work as well?

astrange|3 years ago

The rate for that seems to depend on the person, and IIRC has been suggested to only happen for women.