[mau]

One thing that is underestimated is keep the tools version in sync between your app dev dependencies and pre-commit. This also includes plugins for specific tools (for instance flake8). A solution would be to define the hooks in pre-commit to run the tools inside your venv.

About typings: I agree the eco-system is not mature enough, especially for some frameworks such as Django, but the effort is still valuable and in many cases the static analysis provided by mypy is more useful than not using it at all. So I would suggest to try do your best to make it work.