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beefsack | 3 years ago

This might be related to the TGA approving Moderna's bivalent vaccine[1]. There was a media release by the Department of Health talking about new vaccines recently[2].

[1]: https://www.tga.gov.au/news/media-releases/tga-provisionally...

[2]: https://www.health.gov.au/ministers/the-hon-mark-butler-mp/m...

discuss

yieldcrv|3 years ago

I heard the bivalent vaccines were kind of duds

I do want Covid 2022 vaccines, and seasonal refreshers (not necessarily for myself, just an option over covid 2019 vaccines), but I heard these weren't good enough over the covid 2019 vaccines

Any updated maybe peer reviewed comprehensive studies?

I honestly stopped following. I know the internet has an overrepresentation of people still in their prepper bunkers, but outside is basically the opposite for along time now and more closely matches my view of not needing to have strong opinions about any outcome at all.

birken|3 years ago

Newest study about bivalent effectiveness is probably this one: https://www.cdc.gov/mmwr/volumes/71/wr/mm715152e1.htm

If you want to stay up to date on vaccine effectiveness without wading through a bunch of misinformation, just listen to the weekly "TWIV Clinical update with Dr. Daniel Griffin" podcasts. Here is the most recent one: https://www.microbe.tv/twiv/twiv-967/

For a slightly different perspective on the bivalent boosters, here is Paul Offit (member of the FDA vaccine advisory committee, and one of the two votes against authorizing the bivalent boosters for everybody) talking in detail a couple weeks ago about his current view of the bivalent boosters: https://www.microbe.tv/twiv/twiv-special-offit/.

I would try to summarize what I think is the most accurate view right now based on the science, but honestly there is just too much nuance and too many unknowns to do so concisely, other than I don't think saying they are "duds" makes a whole lot of sense. But I would just listen to the experts on the podcasts who will go into the nuance better than I can.

lucd|3 years ago

"Persons who received the BA.5-containing bivalent booster had better neutralizing activity against all Omicron subvariants (especially against BA.2.75.2, BQ.1.1 and XBB) than those who received 1 or 2 monovalent [original] boosters" https://www.nejm.org/doi/full/10.1056/NEJMc2214293