[piedar]

If you show a skyscraper to an ant, should he abandon his queen because their little hill is too insignificant to matter? Or should he jump back in and build the best damn nest in the city? I just don't think relative scale is really important - even a galaxy-striding star-snacking titan would grapple with the same problem of meaning.

> Nihilists recognize that meaning is not inherent, but rather ascribed by the person experiencing the feeling.

That sounds reasonable, so here's an attempt at a synthesis. The universe is huge and mostly empty, but here we have a tiny patch full of life and self-ascribed meaning. Does the universe prefer life? The part that's alive certainly does! So don't let it fall to ashes just to appease the void. I think that's the best answer a mere mortal can give.