There is data that shows that exercise can reverse-aging, I forget the mechanism. Calorie-restriction can do the same, through a different mechanism. It's reversed up to a limit of course, the sands of time continue on.
Calorie restriction beyond the point of having a normal BMI has never been shown to reverse aging in humans. It's more likely to have the opposite effect due to increased risks from sarcopenia and immune system dysfunction.
nradov|3 years ago