Trillions and trillions of mutations and still the most dangerous H5N1 viruses were created a decade ago by Fouchier and Kawaoka. And how did that help us prepare for the inevitable natural evolution of the same virus?
Sure, but that's only if you restrict it to H5N1 instead of looking at the history of Influenza A and things like the Spanish Flu, which was the most deadly disease in human history and derived from a mutated bird flu.
Even still, H5N1 has repeatedly infected humans in the wild... the most famous case in Hong Kong infecting 18 people and killing 6 of those. So you can make the case that GoF is irresponsible given the stakes, but it seems important to acknowledge that you're basically just hoping these horrific viruses don't mutate as we predict them to.
That would be the case if GoF research was necessary to defend against these viruses, but that’s not the case. AFAIK, GoF research played no part in the development of vaccines and treatments for Covid.
mikeyouse|3 years ago
https://www.nejm.org/doi/full/10.1056/nejmp058281
Even still, H5N1 has repeatedly infected humans in the wild... the most famous case in Hong Kong infecting 18 people and killing 6 of those. So you can make the case that GoF is irresponsible given the stakes, but it seems important to acknowledge that you're basically just hoping these horrific viruses don't mutate as we predict them to.
https://pubmed.ncbi.nlm.nih.gov/11938498/
gensym|3 years ago