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numbasys | 2 years ago

Yes, several hours per image. This resolution is still an achievement. But in vivo images (alive) are much more useful as they enable longitudinal studies, but obviously far more challenging to get anything close to good resolution in a mouse. More like 150 micron in alive, sedated mouse brains, even from 9.4T.

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robwwilliams|2 years ago

Not true so much in mice. Because we use isogenic cohorts we get pseudo-longitudinal data per genome. Ten of you, ten of me scanned every 10 years. And we can do all 20 scans in mice within 1 month of machine time. We just finished scanning 110 mice—half young and half much older—all with balance for genomes and sex.

numbasys|2 years ago

Sure, isogenic cohorts, if the lives of living creatures is valueless, that's fine. Better to work towards in-vivo whenever possible, in my opinion.

VikingCoder|2 years ago

That's really neat. I mean, I'm reminded of the M. Night Shyamalan movie "Old," but yeah, that's really neat.