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chrisamiller | 2 years ago

You're going to want to start with the PCAWG consortium, who looked very closely at viral involvement across a host of cancers. Their numbers:

Cohort: 2,658 cancers across 38 tumor types Findings: Overall, 23 virus genera were detected across 356 patients with cancer (13%)

You can read all of the details here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076016/

I'm not saying that there aren't other mechanisms (sustained inflammation, etc) that might contribute to the aetiology of some other cancers, even without clear viral integrations, but we can state pretty strongly that many cancers are not directly caused by cancer.

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panabee|2 years ago

thank you for sharing, will dig into this.