[allig256]

Alzheimer's is the least likely to kill you of "The Four Horsemen", however it seems to be the most elusive in terms of prevention and treatment.

If deep sleep can contribute to prevention, it seems that yet again exercise is the going to be the best catch-all prophylactic.

[zarzavat]

It may be relatively less common but the slow death it inflicts is highly unpleasant, especially for the people around you. I strongly prefer to die of a heart attack.

[lambdasquirrel]

The worst part is that there isn't a well-defined point where you can say "I'd like to have a medically-assisted suicide" that isn't going to upset people (assuming it were legal). By the time you reach it, you quite possibly won't have the cognitive capacity to request it.

[allig256]

Honestly a heart attack is how I hope I go, over in minutes!

[lynx23]

It would also help if conservatives and believers would stop to work against the right to assisted death. It should be a human right to end ones life if so desired.

[tombert]

Yeah, that's sort of the conclusion I've come to in the last ~6 years. There are so many likely-true benefits to exercise that it almost doesn't matter if a few of them turn out to be false, since no matter what you will probably still benefit from the net result.

[arthur2e5]

The "neurobiological effects of physical exercise" page on Wikipedia gets submitted on HN frequently with few votes, but man is it a fascinating read. Beyond the well-known runner's high, you get cognitive improvements in both short and long term. It even slows down Alzheimer's after you get it, allegedly.

Exercise is no panacea, but people really don't realize how many things it (allegedly) can do, even with super short durations you see in these interval training regimens. Don't force it on people with ME/CFS, sure, but most of us really can and should set aside an hour a week (or less, if you do SIT instead of HIIT).

[Earw0rm]

Good book on the topic: https://www.amazon.co.uk/Miracle-Pill-Ha-Peter-Walker/dp/147...

[hasbot]

Some exercises have the side benefit of being fun!

[tomp]

I’m not worried of dying of Alzheimers.

My grandma had dementia, she was “gone” way before she actually “died”.

[dmix]

> it seems that yet again exercise is the going to be the best catch-all prophylactic.

A novel idea

[mwbajor]

I know doctors that refer to alzheimers as type-3 diabetes. Their gut instinct long ago was that it was indirectly related to insulin regulation. I don't remember exactly how much more (its a large factor), but being overweight and/or having type 2 diabetes makes it much more likely to get alzheimers.