[alecmg]

Started getting RSI symptoms in right hand years ago. Mainly from heavy gaming, but I needed to use mouse at work as well so right hand was not getting any rest.

Switched to using mouse in left hand for work, right hand for gaming. Never looked back. Turns out mouse motorics are almost independent from human handedness.

To comment the article, depending on OS and mice, you will have trouble assigning different orientation to different mice. Usually if you want left hand mouse to have index finger "left" click, it will also switch your right mouse... and trackpad...