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nyc640 | 2 years ago
1. This is a study done on rats and is only a single study, so caveat emptor.
2. They administer 250mg/kg/d Aspartame (human recommended max dose is 50mg/kg/d) based on the claim that "Species correction required a five to six times higher dose in rats than humans, as rats metabolize aspartame faster than humans"
3. Even if you assume effects correlate perfectly to humans, a dosage of 50mg/kg/d in the average American 90kg male corresponds to 22.5 12-oz cans of Diet Coke (200 mg Aspartame) per day for 30 days straight (length of the study).
4. There was a group of rats fed Aspartame at those levels for 1 month, then left to recover for 1 month. The sciatic nerve in these rats recovered significantly, and although it appears the recovery was incomplete, they also state that this difference is not statistically significant. There is also no discussion about whether recovery over a time period > 1 month would have resulted in complete recovery.
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