Not much happened " intellectually and culturally" after the said event!! Modern science was started with the likes of Galileo and Copernicus, was crystallized at the time of Newton and some great improvements happened in the 19th century and very early decades of the 20th. I think the impact of the steam engine and the discovery/development of vaccines in the 18th century are much more impactful than anything humans did after the Manhattan project, apart, maybe, from artificial fertilizers (Oh that was developed before the great war). Planes, cars, sliced bread all came before!!! There is only one exception, computers but these haven't done much to add to mankind happiness. They replaced fax machines and are trying to replace phones helped spread pornography and rage, but so far their effect on humanity is marginal compared to the steam engine or even sliced bread.
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