[fpiacenza]

Important to point out they are talking about harm to self + harm to others. What's not clear is if they are looking at it from a society perspective or from the individual.

From a society perspective any drug with high prevalence of use should top the chart, because of the scale of harm.

In the case of cocaine I would argue that it can't be separated from alcohol. I don't know any cocaine user that doesn't consume it with alcohol, and most do it for the sole purpose of drinking more alcohol. There's a feedback loop where users get very drunk, take a line to feel better and energized, then drink a shit ton again, only to top it off with cocaine, rinse & repeat.