Biodistribution of mRNA COVID-19 vaccines in human breast milk

[vnchr]

> Our findings demonstrate that the COVID-19 vaccine mRNA is not confined to the injection site but spreads systemically and is packaged into BM EVs.

I thought Pfizer tested the vaccine and said this wouldn’t happen.

[astrange]

> However, as only trace quantities are present and a clear translational activity is absent, we believe breastfeeding post-vaccination is safe, especially 48 h after vaccination.

[zolbrek]

That's what was claimed, yes.

[wesapien]

Let's say it's true that it stayed locally, why do we them expect it to create immunity for the body and not just that area?

[reanimus]

Where did you see them claim this?

[notnot]

When I eat a raw vegetable or a piece of sashimi I'm consuming many pieces of mRNA. Does it matter what these molecules encode for? Doesn't my stomach just chop everything up? Would it matter if a baby ate COVID vaccine mRNA?

[cbeach]

While it’s slightly concerning that the baby ingests genetically engineered mRNA that has been untested for infant consumption, the more pressing concern is that mRNA proliferated further than expected in mothers’ bodies.

We were originally told that mRNA vaccines did not spread around the body.

An mRNA vaccine that spreads around the body is problematic, because the body’s own cytotoxic T cells and NK (natural killer) cells will destroy some of our own cells if they express the spike protein (as prompted by the mRNA vaccine). This is particularly problematic in heart cells, where permanent scarring of tissue can occur, weakening the heart and shortening the life of the patient.

[dablweb]

Ah that's where the small print is important.

This isn't "mRNA" this is modified-mRNA (where the name Moderna comes from). Unfortunately they are allowed to abbreviate it as mRNA, which IMO is extremely problematic.

Modified-mRNA uses pseudouridine in some of its base pairs. As such, it is able to remain stable for orders of magnitude more time in many chemical situations.

This practice is incredibly deceptive and lead many in the medical profession to disregard some pretty serious safety issues.

[astrange]

You can tell that it's fine because babies already survive breastfeeding from women who eat meat. Whether or not the mRNA breaks down, it's not harmful.

Babies are actually different from adults here; they get antibodies from breast milk and it supports their immune system, since theirs isn't developed. It's a good thing.

[StephenAmar]

Basically. It’s very unlikely any mRNA would survive intact in the stomach.

[peyton]

Possibly. The article notes:

> Because of their ability to transfer and protect the mRNA, milk EVs have been tested as a vehicle for COVID mRNA oral vaccine

These mRNA fragments are also heavily engineered in a way sashimi mRNA isn’t.

[thenerdhead]

Why is this important? Because two years ago the claim was the opposite in preprint.

We also don’t know if it is safe for this amount to be passed to newborn/infants which is why they urge caution of no BM for two days until further researched.

Newborns especially have fresh microbiomes and are being exposed to new things everyday and especially through BM. The first major time they are exposed to microbes is through delivery. Things like C-section and formula feeding prevent this rich exposure. Usually why we wait until the 6 month mark for certain vaccines, as the microbiome and immune system will be strong enough to fight.

[peyton]

Could be misremembering, but I believe Pfizer turned in no data on breastfeeding in their initial assessment for the EU. If so, a curious omission.