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et2o | 2 years ago

This has been beaten to death in high quality randomized controlled trials in sepsis. Don’t believe a university press release lol. HN is a pretty poor source of health information overall.

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letmevoteplease|2 years ago

The study says: "Randomized controlled trials, however, have shown variable results or even possible harm [10,11,12]. Moreover, current guidelines and a Bayesian re-analysis of a previous trial have led to recommendations not to use intravenous vitamin C in patients with sepsis because of possible harm [13, 14]. Regrettably, these studies used ascorbic acid, a compound associated with the induction of metabolic acidosis and acidemia [15]. This makes it uncertain whether the unclear effects in human sepsis were due to the administration of a suboptimal preparation of the study medication. In contrast, sodium ascorbate (NaAscorbate) has a physiological pH, does not contribute to acidosis, can be given at a much greater dose, and may carry a different efficacy profile [16]."

https://ccforum.biomedcentral.com/articles/10.1186/s13054-02...

olliej|2 years ago

Look, if you can't trust university press releases posted to a tech forum for health advice, who can you trust?

callalex|2 years ago

I take all of my health advice exclusively from statistical language models.

nradov|2 years ago

I usually trust podcasts hosted by comedians and retired athletes.

deeviant|2 years ago

Beaten to death as in proven, or disproven?