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People absolutely flowchart fighting games at a high level. Combos are, unsurprisingly, completely non-interactive in most games, but there's also a term specifically for non-interactive offense: setplay https://glossary.infil.net/?t=Set%20Play

The goal of an optimal strategy in fighting games is generally to reduce the amount that you have to read your opponent as much as possible, ideally to zero. Obviously the developers don't want this to be fully possible, but players generally try to get as close as they can. Even at the highest levels, you can have rounds that go like: canned opening -> combo -> setplay -> combo -> setplay -> combo.