[DougEiffel]

Diabetic mother-in-law is on it. Lost a ton of weight, is moving around better, and when I saw her over the holidays last week I felt she was mentally sharper than before.

My wife has been worried about her mental acuity declining over the last few years and I kept saying I felt like the diabetes was taking a toll on her brain. Perhaps it was? And perhaps it's slowly reversing a bit?

[Hayvok]

Great to hear about your MIL improving!

Last year my wife got the “you need to lose weight now or else” speech from her doctor. Diabetic signs starting to appear in her numbers. I was terrified for her.

12 months of Wegovy and she is down 52 pounds, and all diabetic signs have disappeared. Her doctor is thrilled.

And, (not that this matters much to me) her looking like a million bucks is a nice bonus too.

[khuey]

Type 2 diabetes is known to raise your risk of Alzheimer's and some people think that Alzheimer's is really "type 3" diabetes.

[maxglute]

>I felt she was mentally sharper than before

Losing weight when body has extra fat to cushion caloric deficit can improve a bunch of indicators, for me it's eliminate acid reflux -> better sleep -> less fatigue more sharpness. Losing weight without much fat can do the opposite when body feels full brunt of deficit. Worse sleep, more fatigue, less accuity. I wonder with how accessible these drugs are going to be, if general productivity is going to crash leading up to summer beach bod weather as more people cycles on and off every year.

[kyriakos]

Also anecdotal, but I have a close pre diabetic relative taking it for past 6 months without any positive effects. Looks like it doesn't work on everyone while I see success stories everywhere else.